Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections

Coronaviruses recently emerged as major human pathogens causing outbreaks of severe acute respiratory syndrome and Middle East respiratory syndrome. They utilize the spike (S) glycoprotein anchored in the viral envelope to mediate host attachment and fusion of the viral and cellular membranes to ini...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Xiong, Xiaoli, Tortorici, M. Alejandra, Snijder, Joost, Yoshioka, Craig, Walls, Alexandra C., Li, Wentao, McGuire, Andrew T., Rey, Félix A., Bosch, Berend-Jan, Veesler, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790929/
https://ncbi.nlm.nih.gov/pubmed/29093093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01628-17
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