Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections

Coronaviruses recently emerged as major human pathogens causing outbreaks of severe acute respiratory syndrome and Middle East respiratory syndrome. They utilize the spike (S) glycoprotein anchored in the viral envelope to mediate host attachment and fusion of the viral and cellular membranes to ini...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Xiong, Xiaoli, Tortorici, M. Alejandra, Snijder, Joost, Yoshioka, Craig, Walls, Alexandra C., Li, Wentao, McGuire, Andrew T., Rey, Félix A., Bosch, Berend-Jan, Veesler, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790929/
https://ncbi.nlm.nih.gov/pubmed/29093093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01628-17
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