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Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) glycoprotein initiates infection by promoting fusion of the viral and cellular membranes through conformational changes that remain...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Walls, Alexandra C., Tortorici, M. Alejandra, Snijder, Joost, Xiong, Xiaoli, Bosch, Berend-Jan, Rey, Felix A., Veesler, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651768/
https://ncbi.nlm.nih.gov/pubmed/29073020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708727114
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