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Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) glycoprotein initiates infection by promoting fusion of the viral and cellular membranes through conformational changes that remain...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Walls, Alexandra C., Tortorici, M. Alejandra, Snijder, Joost, Xiong, Xiaoli, Bosch, Berend-Jan, Rey, Felix A., Veesler, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651768/
https://ncbi.nlm.nih.gov/pubmed/29073020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708727114
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