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Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) glycoprotein initiates infection by promoting fusion of the viral and cellular membranes through conformational changes that remain...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Walls, Alexandra C., Tortorici, M. Alejandra, Snijder, Joost, Xiong, Xiaoli, Bosch, Berend-Jan, Rey, Felix A., Veesler, David
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651768/
https://ncbi.nlm.nih.gov/pubmed/29073020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708727114
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