Central ions and lateral asparagine/glutamine zippers stabilize the post-fusion hairpin conformation of the SARS coronavirus spike glycoprotein()

The coronavirus spike glycoprotein is a class I membrane fusion protein with two characteristic heptad repeat regions (HR1 and HR2) in its ectodomain. Here, we report the X-ray structure of a previously characterized HR1/HR2 complex of the severe acute respiratory syndrome coronavirus spike protein....

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Publicado en:Virology
Main Authors: Duquerroy, Stéphane, Vigouroux, Armelle, Rottier, Peter J.M., Rey, Félix A., Jan Bosch, Berend
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Inc. 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111771/
https://ncbi.nlm.nih.gov/pubmed/15840526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.02.022
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