Serine protease inhibitor 6 protects alloreactive T cells from Granzyme B-mediated mitochondrial damage without affecting graft-versus-tumor effect

Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapy for hematologic malignancies. Donor T cells are able to eliminate residual tumor cells after allo-HCT, producing the beneficial graft-versus-tumor (GVT) effect, but can also cause graft-versus-host disease (GV...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Du, Wei, Mohammadpour, Hemn, O'Neill, Rachel E., Kumar, Sandeep, Chen, Chuan, Qiu, Michelle, Mei, Lin, Qiu, Jingxin, McCarthy, Philip L., Lee, Kelvin P., Cao, Xuefang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790363/
https://ncbi.nlm.nih.gov/pubmed/29399396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1397247
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi