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Blockade of host β2-adrenergic receptor enhances graft-versus-tumor effect through modulating antigen presenting cells

Allogeneic hematopoietic cell transplantation (allo-HCT) is a potential curative therapy for hematologic malignancies. Host antigen presenting cells (APCs) are pivotal to the desired graft-versus-tumor (GVT) effect. Recent studies have shown that β2-adrenergic receptor (β2AR) signaling can have an i...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Mohammadpour, Hemn, O’Neil, Rachel, Qiu, Jingxin, McCarthy, Philip L., Repasky, Elizabeth A., Cao, Xuefang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860988/
https://ncbi.nlm.nih.gov/pubmed/29445008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701752
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