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A High-Throughput Small-Molecule Ligand Screen Targeted to Agonists and Antagonists of the G-Protein-Coupled Receptor GPR54

Recent data have shown that the G-protein-coupled receptor GPR54 (also known as KiSS-1 receptor) regulates GnRH release from the hypothalamus. This essential role of GPR54 in controlling the hypothalamic-pituitary-gonadal axis makes it an attractive target for therapeutic intervention in reproductiv...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Kuohung, Wendy, Burnett, Maria, Mukhtyar, Deepa, Schuman, Eli, Ni, Jake, Crowley, William F., Glicksman, Marcie A., Kaiser, Ursula B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790198/
https://ncbi.nlm.nih.gov/pubmed/20460252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057110369701
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