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Kisspeptin/Gpr54-independent GnRH activity in Kiss1 and Gpr54 mutant mice

The kisspeptin/Gpr54 signaling pathway plays a critical role in reproduction by stimulating the secretion of GnRH, yet mice carrying mutations in Kiss1 (which encodes kisspeptin) or Gpr54 exhibit partial sexual maturation. For instance, a proportion of female Kiss1(−/−) and Gpr54(−/−) mice exhibit v...

詳細記述

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書誌詳細
主要な著者: Chan, Yee-Ming, Broder-Fingert, Sarabeth, Wong, Kai Mee, Seminara, Stephanie B.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789182/
https://ncbi.nlm.nih.gov/pubmed/19840236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2009.01926.x
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