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Kisspeptin/Gpr54-independent GnRH activity in Kiss1 and Gpr54 mutant mice
The kisspeptin/Gpr54 signaling pathway plays a critical role in reproduction by stimulating the secretion of GnRH, yet mice carrying mutations in Kiss1 (which encodes kisspeptin) or Gpr54 exhibit partial sexual maturation. For instance, a proportion of female Kiss1(−/−) and Gpr54(−/−) mice exhibit v...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789182/ https://ncbi.nlm.nih.gov/pubmed/19840236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2009.01926.x |
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