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A GPR54-Activating Mutation in a Patient with Central Precocious Puberty
Gonadotropin-dependent, or central, precocious puberty is caused by early maturation of the hypothalamic–pituitary–gonadal axis. In girls, this condition is most often idiopathic. Recently, a G protein–coupled receptor, GPR54, and its ligand, kisspeptin, were described as an excitatory neuroregulato...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859966/ https://ncbi.nlm.nih.gov/pubmed/18272894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa073443 |
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