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Increased hypothalamic GPR54 signaling: A potential mechanism for initiation of puberty in primates

To further study the role of GPR54 signaling in the onset of primate puberty, we used the monkey to examine the ability of kisspeptin-10 to elicit the release of gonadotropin-releasing hormone (GnRH) precociously, and we describe the expression of GPR54 and KiSS-1 in the hypothalamus during the peri...

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Detalhes bibliográficos
Main Authors: Shahab, Muhammad, Mastronardi, Claudio, Seminara, Stephanie B., Crowley, William F., Ojeda, Sergio R., Plant, Tony M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548549/
https://ncbi.nlm.nih.gov/pubmed/15684075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409822102
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