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Kisspeptin and GPR54: Discovery of a Novel Pathway in Reproduction

In order to find novel modulators of gonadotrophin-releasing hormone (GnRH) secretion, genetic tools were employed in patients with idiopathic hypogonadotrophic hypogonadism (IHH). Mutations in a G-protein coupled receptor, GPR54, were identified, making this receptor a genetic determinant and indis...

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Detalhes bibliográficos
Main Authors: Seminara, S. B., Crowley, W. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869294/
https://ncbi.nlm.nih.gov/pubmed/18601695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2008.01731.x
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