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Kisspeptin and GPR54: Discovery of a Novel Pathway in Reproduction
In order to find novel modulators of gonadotrophin-releasing hormone (GnRH) secretion, genetic tools were employed in patients with idiopathic hypogonadotrophic hypogonadism (IHH). Mutations in a G-protein coupled receptor, GPR54, were identified, making this receptor a genetic determinant and indis...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869294/ https://ncbi.nlm.nih.gov/pubmed/18601695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2008.01731.x |
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