A GPR54-Activating Mutation in a Patient with Central Precocious Puberty

Gonadotropin-dependent, or central, precocious puberty is caused by early maturation of the hypothalamic–pituitary–gonadal axis. In girls, this condition is most often idiopathic. Recently, a G protein–coupled receptor, GPR54, and its ligand, kisspeptin, were described as an excitatory neuroregulato...

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Autori principali: Teles, Milena Gurgel, Bianco, Suzy D.C., Brito, Vinicius Nahime, Trarbach, Ericka B., Kuohung, Wendy, Xu, Shuyun, Seminara, Stephanie B., Mendonca, Berenice B., Kaiser, Ursula B., Latronico, Ana Claudia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859966/
https://ncbi.nlm.nih.gov/pubmed/18272894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa073443
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