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Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation
Monoclonal antibodies (mAbs) have been developed as therapeutics, especially for the treatment of cancer, inflammation, and infectious diseases. Because the glycosylation of mAbs in the Fc region influences their interaction with effector cells that kill antibody-targeted cells, and the current meth...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789950/ https://ncbi.nlm.nih.gov/pubmed/29311294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718172115 |
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