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Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington’s disease

Golgi stress response is emerging as a physiologic process of comparable importance to endoplasmic reticulum (ER) and mitochondrial stress responses. However, unlike ER stress, the identity of the signal transduction pathway involved in the Golgi stress response has been elusive. We show that the Go...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sbodio, Juan I., Snyder, Solomon H., Paul, Bindu D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789946/
https://ncbi.nlm.nih.gov/pubmed/29317536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717877115
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