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Transcriptional control of amino acid homeostasis is disrupted in Huntington’s disease
Disturbances in amino acid metabolism, which have been observed in Huntington’s disease (HD), may account for the profound inanition of HD patients. HD is triggered by an expansion of polyglutamine repeats in the protein huntingtin (Htt), impacting diverse cellular processes, ranging from transcript...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978294/ https://ncbi.nlm.nih.gov/pubmed/27436896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608264113 |
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