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Transcriptional control of amino acid homeostasis is disrupted in Huntington’s disease
Disturbances in amino acid metabolism, which have been observed in Huntington’s disease (HD), may account for the profound inanition of HD patients. HD is triggered by an expansion of polyglutamine repeats in the protein huntingtin (Htt), impacting diverse cellular processes, ranging from transcript...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978294/ https://ncbi.nlm.nih.gov/pubmed/27436896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608264113 |
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