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Golgi stress response reprograms cysteine metabolism to confer cytoprotection in Huntington’s disease

Golgi stress response is emerging as a physiologic process of comparable importance to endoplasmic reticulum (ER) and mitochondrial stress responses. However, unlike ER stress, the identity of the signal transduction pathway involved in the Golgi stress response has been elusive. We show that the Go...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Sbodio, Juan I., Snyder, Solomon H., Paul, Bindu D.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789946/
https://ncbi.nlm.nih.gov/pubmed/29317536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717877115
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