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Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease
Huntington’s disease is an autosomal dominant disease associated with a mutation in the gene encoding huntingtin (Htt) leading to expanded polyglutamine repeats of mutant Htt (mHtt) that elicit oxidative stress, neurotoxicity, and motor and behavioural changes(1). Huntington’s disease is characteriz...
Tallennettuna:
| Julkaisussa: | Nature |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4349202/ https://ncbi.nlm.nih.gov/pubmed/24670645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13136 |
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