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Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors
Multipotent hematopoietic progenitors must acquire thymus-homing capacity to initiate T lymphocyte development. Despite its importance, the transcriptional program underlying this process remains elusive. Cbfβ forms transcription factor complexes with Runx proteins, and here we show that Cbfβ2, enco...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789415/ https://ncbi.nlm.nih.gov/pubmed/29343500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171221 |
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