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Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation

Group 2 innate lymphoid cells (ILC2s) have tissue-resident competence and contribute to the pathogenesis of allergic diseases. However, the mechanisms regulating prolonged ILC2-mediated T(H)2 cytokine production under chronic inflammatory conditions are unclear. Here we show that, at homeostasis, Ru...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Miyamoto, Chizuko, Kojo, Satoshi, Yamashita, Motoi, Moro, Kazuyo, Lacaud, Georges, Shiroguchi, Katsuyuki, Taniuchi, Ichiro, Ebihara, Takashi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347616/
https://ncbi.nlm.nih.gov/pubmed/30683858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08365-0
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