Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors

Multipotent hematopoietic progenitors must acquire thymus-homing capacity to initiate T lymphocyte development. Despite its importance, the transcriptional program underlying this process remains elusive. Cbfβ forms transcription factor complexes with Runx proteins, and here we show that Cbfβ2, enco...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Tenno, Mari, Kojo, Satoshi, Lawir, Divine-Fondzenyuy, Hess, Isabell, Shiroguchi, Katsuyuki, Ebihara, Takashi, Endo, Takaho A., Muroi, Sawako, Satoh, Rumi, Kawamoto, Hiroshi, Boehm, Thomas, Taniuchi, Ichiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789415/
https://ncbi.nlm.nih.gov/pubmed/29343500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171221
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