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Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation
Th9 cells are prominently featured in allergic lung inflammation, but the mechanism that regulates IL-9 induction in T helper cells remains poorly defined. Here we demonstrate that formation of super-enhancers (SEs) is critical in robust induction of IL-9 and that assembly of the Il9 SEs in Th cells...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789412/ https://ncbi.nlm.nih.gov/pubmed/29339447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170928 |
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