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The costimulatory receptor OX40 inhibits interleukin-17 expression through activation of repressive chromatin remodeling pathways
T help (Th) 17 cells are prominently featured in multiple autoimmune diseases, but the regulatory mechanisms that control Th17 cell responses are poorly defined. Here we found that stimulation of OX40 triggered a robust chromatin remodeling response and produced a “closed” chromatin structure at int...
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| Publicado no: | Immunity |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917494/ https://ncbi.nlm.nih.gov/pubmed/27317259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.05.013 |
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