MELK is a novel therapeutic target in high-risk neuroblastoma

Maternal embryonic leucine zipper kinase (MELK) is known to modulate intracellular signaling and control cellular processes. However, the role of MELK in oncogenesis is not well defined. In this study, using two microarray datasets of neuroblastoma (NB) patients, we identified that MELK expression i...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Guan, Shan, Lu, Jiaxiong, Zhao, Yanling, Yu, Yang, Li, Hui, Chen, Zhenghu, Shi, Zhongcheng, Liang, Haoqian, Wang, Mopei, Guo, Kevin, Chen, Xiangmei, Sun, Wenjing, Bieerkehazhi, Shayahati, Xu, Xin, Sun, Surong, Agarwal, Saurabh, Yang, Jianhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788662/
https://ncbi.nlm.nih.gov/pubmed/29416794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23515
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