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Co-Receptors and Recognition of Self at the Immunological Synapse

The co-receptors CD4 and CD8 are important in the activation of T cells, primarily because of their ability to interact with the proteins of the MHC, enhancing recognition of the MHC–peptide complex by the T cell receptor (TCR). An antigen-presenting cell presents a small number of antigenic peptide...

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Bibliographic Details
Published in:Curr Top Microbiol Immunol
Main Authors: Gascoigne, Nicholas R.J., Zal, Tomasz, Yachi, Pia P., Hoerter, John A.H.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788015/
https://ncbi.nlm.nih.gov/pubmed/19960314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-03858-7_9
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