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The TCR's α-CPM promotes close approximation of the CD8 co-receptor allowing efficient signal initiation
The CD8 co-receptor contributes to the recognition of peptide-MHC (pMHC) ligands by stabilizing the TCR-pMHC interaction and enabling efficient signaling initiation. It is unclear though, which structural elements of the TCR ensure a productive association of the co-receptor. The α-chain connecting...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764738/ https://ncbi.nlm.nih.gov/pubmed/18523287 |
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