Polymyxin B in combination with meropenem against carbapenemase-producing Klebsiella pneumoniae: pharmacodynamics and morphological changes

Combination therapy provides a useful therapeutic approach to overcome resistance until new antibiotics become available. In this study, the pharmacodynamics, including the morphological effects, of polymyxin B (PMB) and meropenem alone and in combination against KPC-producing Klebsiella pneumoniae...

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Veröffentlicht in:Int J Antimicrob Agents
Hauptverfasser: Sharma, Rajnikant, Patel, Saloni, Abboud, Cely, Diep, John, Ly, Neang S., Pogue, Jason M., Kaye, Keith S., Li, Jian, Rao, Gauri G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786158/
https://ncbi.nlm.nih.gov/pubmed/28040408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2016.10.025
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