SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells

Single-stranded oligonucleotides (ssOligos) are efficiently taken up by living cells without the use of transfection reagents. This phenomenon called ‘gymnosis’ enables the sequence-specific silencing of target genes in various types of cells. Several antisense ssOligos are used for the treatment of...

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Dettagli Bibliografici
Pubblicato in:RNA Biol
Autori principali: Takahashi, Masayuki, Contu, Viorica Raluca, Kabuta, Chihana, Hase, Katsunori, Fujiwara, Yuuki, Wada, Keiji, Kabuta, Tomohiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785214/
https://ncbi.nlm.nih.gov/pubmed/28277980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1302641
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