Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes

Lysosomes are thought to be the major intracellular compartment for the degradation of macromolecules. We recently identified a novel type of autophagy, RNautophagy, where RNA is directly taken up by lysosomes in an ATP-dependent manner and degraded. However, the mechanism of RNA translocation acros...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Aizawa, Shu, Fujiwara, Yuuki, Contu, Viorica Raluca, Hase, Katsunori, Takahashi, Masayuki, Kikuchi, Hisae, Kabuta, Chihana, Wada, Keiji, Kabuta, Tomohiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Basic Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836006/
https://ncbi.nlm.nih.gov/pubmed/27046251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1145325
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