Direct uptake and degradation of DNA by lysosomes

Lysosomes contain various hydrolases that can degrade proteins, lipids, nucleic acids and carbohydrates. We recently discovered “RNautophagy,” an autophagic pathway in which RNA is directly taken up by lysosomes and degraded. A lysosomal membrane protein, LAMP2C, a splice variant of LAMP2, binds to...

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Detalhes bibliográficos
Main Authors: Fujiwara, Yuuki, Kikuchi, Hisae, Aizawa, Shu, Furuta, Akiko, Hatanaka, Yusuke, Konya, Chiho, Uchida, Kenko, Wada, Keiji, Kabuta, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Basic Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748189/
https://ncbi.nlm.nih.gov/pubmed/23839276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24880
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