Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes

Lysosomes degrade macromolecules such as proteins and nucleic acids. We previously identified 2 novel types of autophagy, RNautophagy and DNautophagy, where lysosomes directly take up RNA and DNA, in an ATP-dependent manner, for degradation. We have also reported that SIDT2 (SID1 transmembrane famil...

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Publicado no:Autophagy
Main Authors: Aizawa, Shu, Contu, Viorica Raluca, Fujiwara, Yuuki, Hase, Katsunori, Kikuchi, Hisae, Kabuta, Chihana, Wada, Keiji, Kabuta, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245770/
https://ncbi.nlm.nih.gov/pubmed/27846365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1248019
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