Cytosolic domain of SIDT2 carries an arginine-rich motif that binds to RNA/DNA and is important for the direct transport of nucleic acids into lysosomes

RNautophagy and DNautophagy (RDA) are unconventional autophagic pathways where nucleic acids are directly transported through the lysosomal membrane, then degraded inside lysosomes. We have previously shown that bitopic protein LAMP2C and putative RNA transporter SIDT2, both lysosomal membrane prote...

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Udgivet i:Autophagy
Main Authors: Hase, Katsunori, Contu, Viorica Raluca, Kabuta, Chihana, Sakai, Ryohei, Takahashi, Masayuki, Kataoka, Naoyuki, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Fujiwara, Yuuki, Wada, Keiji, Kabuta, Tomohiro
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595612/
https://ncbi.nlm.nih.gov/pubmed/31944164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1712109
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