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Insights into neuroepigenetics through human histone deacetylase PET imaging
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundamental knowledge gap exists regarding the expression...
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| Publicado en: | Sci Transl Med |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5784409/ https://ncbi.nlm.nih.gov/pubmed/27510902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf7551 |
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