Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus

Mutations in the beta-subunit of bacterial RNA polymerase (RpoB) cause resistance to rifampin (Rif(r)), a critical antibiotic for treatment of multidrug-resistant Staphylococcus aureus. In vitro studies have shown that RpoB mutations confer decreased susceptibility to other antibiotics, but the clin...

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Detaylı Bibliyografya
Yayımlandı:mSphere
Asıl Yazarlar: Guérillot, Romain, Gonçalves da Silva, Anders, Monk, Ian, Giulieri, Stefano, Tomita, Takehiro, Alison, Eloise, Porter, Jessica, Pidot, Sacha, Gao, Wei, Peleg, Anton Y., Seemann, Torsten, Stinear, Timothy P., Howden, Benjamin P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784246/
https://ncbi.nlm.nih.gov/pubmed/29404415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00550-17
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