Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)

Mutation acquisition is a major mechanism of bacterial antibiotic resistance that remains insufficiently characterised. Here we present RM-seq, a new amplicon-based deep sequencing workflow based on a molecular barcoding technique adapted from Low Error Amplicon sequencing (LEA-seq). RM-seq allows d...

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發表在:Genome Med
Main Authors: Guérillot, Romain, Li, Lucy, Baines, Sarah, Howden, Brian, Schultz, Mark B., Seemann, Torsten, Monk, Ian, Pidot, Sacha J., Gao, Wei, Giulieri, Stefano, Gonçalves da Silva, Anders, D’Agata, Anthony, Tomita, Takehiro, Peleg, Anton Y., Stinear, Timothy P., Howden, Benjamin P.
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
主題:
Method
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117896/
https://ncbi.nlm.nih.gov/pubmed/30165908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0572-z
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