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Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus
Mutations in the beta-subunit of bacterial RNA polymerase (RpoB) cause resistance to rifampin (Rif(r)), a critical antibiotic for treatment of multidrug-resistant Staphylococcus aureus. In vitro studies have shown that RpoB mutations confer decreased susceptibility to other antibiotics, but the clin...
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| Veröffentlicht in: | mSphere |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5784246/ https://ncbi.nlm.nih.gov/pubmed/29404415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00550-17 |
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