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Conformational folding and disulfide bonding drive distinct stages of protein structure formation

The causal relationship between conformational folding and disulfide bonding in protein oxidative folding remains incompletely defined. Here we show a stage-dependent interplay between the two events in oxidative folding of C-reactive protein (CRP) in live cells. CRP is composed of five identical su...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Lv, Jian-Min, Lü, Shou-Qin, Liu, Zu-Pei, Zhang, Juan, Gao, Bo-Xuan, Yao, Zhen-Yu, Wu, Yue-Xin, Potempa, Lawrence A., Ji, Shang-Rong, Long, Mian, Wu, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784126/
https://ncbi.nlm.nih.gov/pubmed/29367639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20014-y
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