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Conformational folding and disulfide bonding drive distinct stages of protein structure formation

The causal relationship between conformational folding and disulfide bonding in protein oxidative folding remains incompletely defined. Here we show a stage-dependent interplay between the two events in oxidative folding of C-reactive protein (CRP) in live cells. CRP is composed of five identical su...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Lv, Jian-Min, Lü, Shou-Qin, Liu, Zu-Pei, Zhang, Juan, Gao, Bo-Xuan, Yao, Zhen-Yu, Wu, Yue-Xin, Potempa, Lawrence A., Ji, Shang-Rong, Long, Mian, Wu, Yi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784126/
https://ncbi.nlm.nih.gov/pubmed/29367639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20014-y
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