Conformational folding and disulfide bonding drive distinct stages of protein structure formation

The causal relationship between conformational folding and disulfide bonding in protein oxidative folding remains incompletely defined. Here we show a stage-dependent interplay between the two events in oxidative folding of C-reactive protein (CRP) in live cells. CRP is composed of five identical su...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Lv, Jian-Min, Lü, Shou-Qin, Liu, Zu-Pei, Zhang, Juan, Gao, Bo-Xuan, Yao, Zhen-Yu, Wu, Yue-Xin, Potempa, Lawrence A., Ji, Shang-Rong, Long, Mian, Wu, Yi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784126/
https://ncbi.nlm.nih.gov/pubmed/29367639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20014-y
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