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Celluar Folding Determinants and Conformational Plasticity of Native C-Reactive Protein

C-reactive protein (CRP) is an acute phase reactant secreted by hepatocytes as a pentamer. The structure formation of pentameric CRP has been demonstrated to proceed in a stepwise manner in live cells. Here, we further dissect the sequence determinants that underlie the key steps in cellular folding...

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Vydáno v:Front Immunol
Hlavní autoři: Lv, Jian-Min, Chen, Jun-Yao, Liu, Zu-Pei, Yao, Zhen-Yu, Wu, Yue-Xin, Tong, Cheng-Sen, Cheng, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7137756/
https://ncbi.nlm.nih.gov/pubmed/32296446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00583
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