Conformational folding and disulfide bonding drive distinct stages of protein structure formation

The causal relationship between conformational folding and disulfide bonding in protein oxidative folding remains incompletely defined. Here we show a stage-dependent interplay between the two events in oxidative folding of C-reactive protein (CRP) in live cells. CRP is composed of five identical su...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Lv, Jian-Min, Lü, Shou-Qin, Liu, Zu-Pei, Zhang, Juan, Gao, Bo-Xuan, Yao, Zhen-Yu, Wu, Yue-Xin, Potempa, Lawrence A., Ji, Shang-Rong, Long, Mian, Wu, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784126/
https://ncbi.nlm.nih.gov/pubmed/29367639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20014-y
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