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Chronic impairment of ERK signaling in glutamatergic neurons of the forebrain does not affect spatial memory retention and LTP in the same manner as acute blockade of the ERK pathway

The ERK/MAPK signaling pathway has been extensively studied in the context of learning and memory. Defects in this pathway underlie genetic diseases associated with intellectual disability, including impaired learning and memory. Numerous studies have investigated the impact of acute ERK/MAPK inhibi...

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發表在:Hippocampus
Main Authors: Vithayathil, Joseph, Pucilowska, Joanna, Friel, David, Landreth, Gary E.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783323/
https://ncbi.nlm.nih.gov/pubmed/28833860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22769
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