Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation

The ERK/MAPK pathway is an important developmental signaling pathway. Mutations in upstream elements of this pathway result in neuro-cardio-facial cutaneous (NCFC) syndromes, which are typified by impaired neurocognitive abilities that are reliant upon hippocampal function. The role of ERK signaling...

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Publicado en:J Neurosci
Main Authors: Vithayathil, Joseph, Pucilowska, Joanna, Goodnough, L. Henry, Atit, Radhika P., Landreth, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412899/
https://ncbi.nlm.nih.gov/pubmed/25926459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4196-14.2015
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