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Chronic impairment of ERK signaling in glutamatergic neurons of the forebrain does not affect spatial memory retention and LTP in the same manner as acute blockade of the ERK pathway

The ERK/MAPK signaling pathway has been extensively studied in the context of learning and memory. Defects in this pathway underlie genetic diseases associated with intellectual disability, including impaired learning and memory. Numerous studies have investigated the impact of acute ERK/MAPK inhibi...

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Vydáno v:Hippocampus
Hlavní autoři: Vithayathil, Joseph, Pucilowska, Joanna, Friel, David, Landreth, Gary E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783323/
https://ncbi.nlm.nih.gov/pubmed/28833860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22769
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