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OS4.5 Magnetic resonance spectroscopy for in vivo detection of 2-hydroxyglutarate in lower-grade gliomas
INTRODUCTION: Isocitrate dehydrogenase 1 (IDH1) and IDH2 mutations are detected in up to 75% grade II-III (lower-grade) gliomas (LGG). IDH1/2 mutations result in 2-hydroxyglutarate (2HG) synthesis. 2HG screening is a useful marker to detect the presence of IDH1/2 mutations. Magnetic resonance spectr...
Gespeichert in:
| Veröffentlicht in: | Neuro Oncol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782531/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.031 |
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