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OS4.1 Detection of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for diagnosing IDH1 mutant glioma
INTRODUCTION: Mutations in the isocitrate dehydrogenase 1 (IDH1) gene are frequently observed in low-grade glioma and secondary glioblastoma and strongly associated with the accumulation of 2-hydroxyglutarate (2HG), which is a valuable diagnostic and prognostic biomarker of IDH1 mutant glioma. Howev...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782527/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.027 |
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