Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma

BACKGROUND: Mutations in the isocitrate dehydrogenase 1 (IDH1) gene that are frequently observed in low-grade glioma are strongly associated with the accumulation of 2-hydroxyglutarate (2HG), which is a valuable diagnostic and prognostic biomarker of IDH1 mutant glioma. However, conventional MR spec...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Nagashima, Hiroaki, Tanaka, Kazuhiro, Sasayama, Takashi, Irino, Yasuhiro, Sato, Naoko, Takeuchi, Yukiko, Kyotani, Katsusuke, Mukasa, Akitake, Mizukawa, Katsu, Sakata, Junichi, Yamamoto, Yusuke, Hosoda, Kohkichi, Itoh, Tomoo, Sasaki, Ryohei, Kohmura, Eiji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063515/
https://ncbi.nlm.nih.gov/pubmed/27154922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now090
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