OS2.6 Identification of IDH1R132H-specific T cell receptors from a humanized mouse model and from glioma patients treated with an IDH1R132H-specific peptide vaccine

Central to clinically relevant immunotherapy of gliomas are the discovery of tumor-specific antigens and the development of therapeutic strategies that effectively exploit them. One such example is the mutation in the gene encoding for isocitrate dehydrogenase 1 (IDH1). The point mutation IDH1R132H...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Sanghvi, K., Green, E., Bunse, T., Bunse, L., Sahm, F., Omokoko, T., Sahin, U., Schmitt, M., Wick, W., Platten, M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
OS2 Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782516/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.016
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