Proximity ligation assay evaluates IDH1(R132H) presentation in gliomas

For a targeted cancer vaccine to be effective, the antigen of interest needs to be naturally processed and presented on MHC by the target cell or an antigen-presenting cell (APC) in the tumor stroma. The presence of these characteristics is often assumed based on animal models, evaluation of antigen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Bunse, Lukas, Schumacher, Theresa, Sahm, Felix, Pusch, Stefan, Oezen, Iris, Rauschenbach, Katharina, Gonzalez, Marina, Solecki, Gergely, Osswald, Matthias, Capper, David, Wiestler, Benedikt, Winkler, Frank, Herold-Mende, Christel, von Deimling, Andreas, Wick, Wolfgang, Platten, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
Schlagworte:
Technical Advance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319432/
https://ncbi.nlm.nih.gov/pubmed/25555220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77780
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