OS2.1 Immune responses to a mutation-specific peptide vaccine targeting IDH1R132H in patients with IDH1R132H-mutated gliomas

Immunotherapeutic concepts for brain tumors have been hampered by lack of selective measures to target the CNS and lack of truly tumor-specific antigens. But the concept of an immune privileged CNS has to be questioned due to survey of the brain by specific T-cells, CNS autoimmunity and presence of...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Bunse, T., Bunse, L., Sahm, F., Omokoko, T., Stevanovic, S., Deimling, A. von, Sahin, U., Schmitt, M., Wick, W., Platten, M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
OS2 Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782511/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.011
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