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OS10.2 R-2-Hydroxyglutarate shapes the immune microenvironment in IDH1-mutant gliomas
Background: IDH1-mutant tumors form the majority of grade II and grade III gliomas, qualifying as a new entity in the 2016 WHO classification of CNS tumors. We have previously shown that a peptide vaccine encoding the IDH1(R132H) epitope evokes an MHC II-restricted CD4+ T Helper-1 cell (Th1) immune...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463695/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.070 |
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